Membrane protein FasL not through apoptosis way promote autoimmune and tumor formation

For FasL (Fas ligand) across the membrane proteins in the immune regulation is an important role in the tumor necrosis factor of a member in the family. The combination of its receptor FasL apoptosis, but it was not clear cell death FasL cell function of how important. Genes associated with eliminate mutant mice (they lack the secretion FasL, but express normal level of combined with film FasL; or lack FasL, combined with film but still producing secretion FasL) do the experiments showed that, soluble FasL through does not involve apoptosis promote autoimmune and tumor formation.

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