Isocitrate dehydrogenase

Isocitrate dehydrogenase

Product Description:
Isocitrate dehydrogenase is an enzyme that participates in the citric acid cycle. It catalyzes the third step of the cycle: the oxidative decarboxylation of isocitrate, producing alpha-ketoglutarate (α-ketoglutarate) and CO2 while converting NAD+ to NADH. Another isoform of the enzyme catalyzes the same reaction, however this reaction is unrelated to the citric acid cycle, is carried out in the cytosol as well as the mitochondrion and peroxisome and uses NADP+ as a cofactor instead of NAD+.

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