PECI: Human peroxisomal Delta3, Delta2-enoyl CoA isomerase
PDB Code: 2F6Q
Utilization of fatty acids as energy source is a fundamental process in all mammals and involves the evolutionarily conserved β-oxidation pathway of acyl CoAs, which occurs in mitochondria and peroxisomes. The metabolism of saturated fatty acids requires 4 enzyme activities intrinsic to the β-oxidation pathway. However, the metabolism of ubiquitously occurring unsaturated fatty acids requires auxiliary enzymes in addition to the spiral of β-oxidation enzymes. These auxiliary activities consist of Δ3,5, Δ2,4-dienoyl CoA isomerase, Δ2,4 dienoyl CoA isomerase and Δ3 , Δ2 - enoyl CoA isomerase (PECI). PECI is an essential link for peroxisomal b -oxidation of saturated and unsaturated fatty acids. The enzyme catalyzes the isomerization of cis- or trans configured double bonds from the C3 position of acyl-CoAs to yield the trans-2 double bond configured fatty acyl CoA, which can be directed into the β-oxidation pathway.
Welcome to buy
This form is unable to receive your inquiry from aol, hotmail, gmail or others but company email address.After send online enquiry, we will reply you as soon as possible, if not get any response on time please contact us by Tel or Email.
1. Email: firstname.lastname@example.org
2. Tel: +86 592 5365887
3.WhatsApp: +86 189 6515 7632
4. Send enquiry online
You may also be interested in :
For more information of product, please send the email to email@example.com