AASDHPPT: Human 4’-phosphopantetheinyl transferase
PDB Code: 2C43
AASDHPPT catalyzes the transfer of the 4’-phosphopantetheine moiety of coenzyme A to different carrier proteins, the most significant being the acyl carrier protein domains of cytosolic and mitochondrial fatty acid synthase enzymes. This modification of acyl-carrier proteins associated with type I and II fatty acids synthases is essential for lipid synthesis pathways.
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